System, device, and methods for real-time screening of live cells, biomarkers, and chemical signatures

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United States of America Patent

PATENT NO 7956328
APP PUB NO 20110024630A1
SERIAL NO

12511833

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Abstract

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An ATR-FTIR device and system are described that defect live-cell responses to stimuli and perturbations in real-time. The system and device can monitor perturbations resulting from exposures to various physical, chemical, and biological materials in real-time, as well as those sustained over a long period of time, including those associated with stimuli having unknown modes-of-action (e.g. nanoparticles). The device and system can also be used to identify specific chemical species or substances that profile cellular responses to these perturbations.

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Patent Owner(s)

  • BATTELLE MEMORIAL INSTITUTE

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Addleman, R Shane Benton City, US 2 42
Riley, Brian J West Richland, US 6 38
Sacksteder, Colette A West Richland, US 2 52
Sundaram, S Kamakshi Richland, US 4 42
Weber, Thomas J Richland, US 17 229

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