Compositions and methods for robust dynamic metabolic control of a biofermentation process

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United States of America

PATENT NO 11268111
APP PUB NO 20200056211A1
SERIAL NO

16487542

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Abstract

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The present disclosure provides compositions and methods for rapid production of chemicals in genetically engineered microorganisms in a large scale. Also provided herein is a high-throughput metabolic engineering platform enabling the rapid optimization of microbial production strains. The platform, which bridges a gap between current in vivo and in vitro bio-production approaches, relies on dynamic minimization of the active metabolic network.

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Patent Owner(s)

  • DUKE UNIVERSITY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Lynch, Michael David Durham, US 19 48
Ye, Zhixia Raleigh, US 14 30

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