Compositions containing and methods of using 1-aminoindan and derivatives thereof and process for preparing optically active 1-aminoindan derivatives

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United States of America Patent

PATENT NO 5914349
SERIAL NO

08485688

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Abstract

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Novel derivatives of 1-aminoindan and their salts are described. Optically active 1-aminoindan derivatives are prepared by reacting a N-benzyl analog of the desired compound with an enantiomer of mandelic acid. Parkinson's disease, dementia, epilepsy, convulsions, or seizures are treated by administering a compound of the formula:

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Patent Owner(s)

  • TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD.;TEVA PHARMACEUTICAL INDUSTRIES LTD.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cohen, Sasson Tel Aviv, IL 15 290
Finberg, John P M Tivon, IL 19 823
Herzig, Yaacov Raanana, IL 22 438
Levy, Ruth Tel Aviv, IL 60 1457
Shirvan, Mitchell Jerusalem, IL 24 220
Sterling, Jeff Jerusalem, IL 12 377
Veinberg, Alex Rehovot, IL 16 623
Youdim, Moussa B H Haifa, IL 30 858

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