Therapeutic ion channel blocking agents and methods of use thereof

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United States of America Patent

PATENT NO 7507839
APP PUB NO 20050261301A1
SERIAL NO

10507925

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Various divalent ligands based on khellinone derivatives are described. These derivatives can be useful in the modulation of potassium channel activity in cells, including among others Kv1.3 channels found in T-cells. The compounds may also be useful in the treatment or prevention of autoimmune and inflammatory diseases, including multiple sclerosis.

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Patent Owner(s)

  • WALTER AND ELIZA HALL INSTITUTE OF MEDICAL, THE

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Baell, Jonathan B Parkville , AU 8 37
Chandy, George K Irvine , US 6 20
Harvey, Andrew J Parkville , AU 4 4
Norton, Raymond S Parkville , AU 5 44
Wulff, Heike Irvine , US 16 14

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