Cyclic dipeptides and azetidinone compounds and their use in treating CNS injury and neurodegenerative disorders

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United States of America Patent

PATENT NO 7202279
SERIAL NO

09246307

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Abstract

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The present invention provides 4-substituted-2-azetidinone compounds, bicyclic 2-5-diketopiperazine compounds, and pharmaceutical compositions thereof that are potent, safe and effective neuroprotective agents. Due to their strong central nervous system (CNS) activity, the compounds can be used to enhance memory and to treat a variety of neurological disorders. The compounds are particularly useful for treating neurological disorders caused by, or associated with, CNS trauma.

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Patent Owner(s)

  • GEORGETOWN UNIVERSITY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Araldi, Gian Luca San Diego, CA 31 261
Faden, Alan I Washington, DC 7 46
Kozikowski, Alan P Princeton, NJ 80 1177

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