Inhibitors of serine proteases, particularly HCV NS3-NS4A protease
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United States of America Patent
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Jul 16, 2013
Grant Date -
Feb 21, 2008
app pub date -
May 22, 2007
filing date -
Oct 24, 2001
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Abstract
The present invention relates to peptidomimetic compounds that inhibit serine protease activity, particularly the activity of hepatitis C virus NS3-NS4A protease. As such, they act by interfering with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The invention further relates to compositions comprising these compounds either for ex vivo use or for administration to a patient suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a patient by administering a composition comprising a compound of this invention.
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