MAGE-A3 peptides presented by HLA class II molecules
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United States of America Patent
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May 13, 2008
Grant Date -
Sep 21, 2006
app pub date -
May 23, 2006
filing date -
May 18, 2001
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Abstract
The invention describes HLA class II binding peptides encoded by the MAGE-A3 tumor associated gene, as well as nucleic acids encoding such peptides and antibodies relating thereto. The peptides stimulate the activity and proliferation of CD4.sup.+ T lymphocytes. Methods and products also are provided for diagnosing and treating conditions characterized by expression of the MAGE-A3 gene.
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