N-substituted tricyclic 1-aminopyrazoles as inhibitors for the treatment of cell proliferative disorders

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United States of America Patent

PATENT NO 7795440
APP PUB NO 20070142305A1
SERIAL NO

11657912

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention is directed to N-substituted tricyclic 3-AMINOPYRAZOLE derivatives, which are useful as inhibitors of platelet-derived growth factor receptor (PDGF-R) kinase, and methods for the preparation of said derivatives. The present invention is further directed to pharmaceutical compositions comprising the compounds of the present invention and to methods for treating conditions such as tumors and other cell proliferative disorders.

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Patent Owner(s)

  • JANSSEN PHARMACEUTICA NV

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Brunmark, Bengt Anders LaJolla, US 2 10
Emanuel, Stuart Doylestown, US 25 538
Galemmo,, Jr Robert A Collegeville, US 11 9
Ho, Chih Yung Lansdale, US 28 319
Johnson, Dana L Upper Black Eddy, US 33 410
Ludovici, Donald W Quakertown, US 17 83
Maharoof, Umar North Wales, US 15 140
Mei, Jay M North Wales, US 6 18
Sechler, Jan L Doylestown, US 5 79
Strobel, Eric D Hatboro, US 4 23
Tuman, Robert W Chalfont, US 19 153
Yen, Hwa Kwo Malvern, US 2 10

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