Particle agglutination in a tip
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United States of America Patent
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Dec 14, 2010
Issued Date -
N/A
app pub date -
Mar 11, 2008
filing date -
Mar 11, 2008
priority date (Note) -
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Abstract
An apparatus and a related method for performing particle agglutination reactions in a single, disposable probe tip are disclosed. The probe tip includes a sample cavity for sample acquisition, at least one flanking cavity for the capture of particles by centrifugation or other means, a transition zone for the mixing of the sample with reagents for agglutination and a detection zone for the optical detection of particle agglutination. A mechanism may be attached to the probe tip for the controlled movement of fluids through the internal volume of the probe tip. The probe tip is particularly useful for the automation of high-throughput agglutination-type assays.
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