Assays for diagnosis of thrombophilic disease
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United States of America Patent
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Aug 7, 2007
Grant Date -
Sep 22, 2005
app pub date -
Jan 3, 2005
filing date -
Jul 11, 1997
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The present invention provides methods for diagnosing and/or monitoring thrombophilic disease in a patient that can result from the antiphospholipid antibody syndrome (aPL syndrome). The methods of the invention are premised on the inhibition of binding of an anticoagulant protein, annexin, preferably annexin-V, to phospholipids by antiphospholipid (aPL) antibodies in a patient blood sample.
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