Vascular endothelial growth factor 2
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United States of America Patent
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Dec 26, 2006
Grant Date -
Jan 9, 2003
app pub date -
Aug 24, 2001
filing date -
Mar 8, 1994
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Disclosed are human VEGF2 polypeptides, biologically active, diagnostically or therapeutically useful fragments, analogs, or derivatives thereof, and DNA (RNA) encoding such VEGF2 polypeptides. Also provided are procedures for producing such polypeptides by recombinant techniques and antibodies and antagonists against such polypeptides. Such polypeptides may be used therapeutically for stimulating wound healing and for vascular tissue repair. Also provided are methods of using the antibodies and antagonists to inhibit tumor angiogenesis and thus tumor growth, inflammation, diabetic retinopathy, rheumatoid arthritis, and psoriasis.
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