Stable cell lines and methods for evaluating gastrointestinal absorption of chemicals
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United States of America Patent
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Sep 14, 2010
Grant Date -
May 29, 2008
app pub date -
Nov 9, 2007
filing date -
Nov 10, 2006
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Abstract
Nucleic acids and vectors for interfering with the expression of membrane efflux transport proteins in cells that express such proteins are provided. Also provided are cells and cell lines comprising such nucleic acids and vectors. Methods for screening chemicals and biomolecules for gastrointestinal absorption in animals, and kits for practicing such methods are also provided.
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