Anti-CD25 for tumour specific cell depletion

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United States of America Patent

PATENT NO 11697688
APP PUB NO 20210009704A1
SERIAL NO

16979935

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present disclosure provides antibody sequences found in antibodies that bind to human CD25, in particular an anti CD25-a-674 antibody which do not block the binding of CD25 to IL-2 or IL-2 signalling. The claimed antibody binds to the epitopes: QCVQGYRA and RWTQPQLICTG on CD25 Antibodies and antigen-binding portions thereof including such sequences can be used in pharmaceutical compositions and methods of treatment, in particular for treating cancer.

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Patent Owner(s)

  • TUSK THERAPEUTICS LTD.; CANCER RESEARCH TECHNOLOGY LIMITED

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Brown, Mark Hertfordshire, GB 95 1022
Geoghegan, James Lyme, US 16 193
Goubier, Anne Hertfordshire, GB 23 130
Goyenechea, Corzo Beatriz Hertfordshire, GB 20 130
Merchiers, Pascal Hertfordshire, GB 43 291
Moulder, Kevin Hertfordshire, GB 34 266
Prinz, Bianka Lebanon, US 106 298
Quezada, Sergio London, GB 25 249
Salimu, Josephine Hertfordshire, GB 21 130

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