Anti-CCR1 antibodies and methods of use thereof
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United States of America Patent
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Jun 19, 2007
Grant Date -
Dec 30, 2004
app pub date -
Apr 26, 2004
filing date -
Jan 29, 1999
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The present invention relates to an antibody or functional fragment thereof which binds to a mammalian (e.g., human) CC-chemokine receptor 1 (CCR1) or a portion of the receptor and blocks binding of a ligand to the receptor. The invention further relates to a method of inhibiting the interaction of a cell bearing mammalian CCR1 with a ligand thereof, and to use of the antibodies and fragments in research, therapeutic, prophylactic and diagnostic methods.
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