IL-1β binding antibodies and fragments thereof
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United States of America Patent
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May 12, 2009
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app pub date -
Jun 21, 2006
filing date -
Jun 21, 2005
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Abstract
An IL-1β binding antibody or IL-1β binding fragment thereof comprising the amino acid sequence of SEQ ID NO: 2, and related nucleic acids, vectors, cells, and compositions, as well as method of using same to treat or prevent a disease, and a method of preparing an affinity matured IL-1β binding polypeptide. IL-1β binding antibodies or IL-1β binding fragments thereof are provided which have desirable affinity and potency.
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