Immunochemical detection of an explosive substance in the gas phase through surface plasmon resonance spectroscopy
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United States of America Patent
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Jun 3, 2003
Grant Date -
N/A
app pub date -
Feb 26, 1999
filing date -
Aug 5, 1998
priority date (Note) -
Expired
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Abstract
The biosensor involves a specially designed surface which can be optically coupled to a Surface Plasmon Resonance spectrometer. The key components of the biosensor are a bimetallic layer, a self assembled monolayer of chemicals and a layer of biomolecules such as special antibodies. The innovative bimetallic layer combines the sensitivity of silver metal and durability of gold and thus make it an ideal biosensor layer not only for a low volatility gas phase detection but also for a liquid phase detection. The successful application of the biosensor in high explosive substance detection proves that the biosensor is a sensitive and highly specific device for security and anti-terrorism applications, when it is combined with a Surface Plasmon Resonance Spectroscope.
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