High voltage nanosecond pulse generator using fast recovery diodes for cell electro-manipulation
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United States of America Patent
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Mar 8, 2011
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N/A
app pub date -
Feb 9, 2010
filing date -
Apr 22, 2005
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Abstract
A pulse generator circuit may include a diode configured to operate as an opening switch, a tank circuit in series with the diode having an admittance that is switchable from a first value to a second value that is different from the first value, and a switching system configured to cause the tank circuit to switch between the first value and the second value. The diode may saturate in less than 100 nanoseconds. A saturable core transformer may operate as a switch that controls the opening of the diode. The pulse generator may generate a plurality of pulses, each having a length of no more than 3 nanoseconds and an amplitude of at least 1 kilovolt. Electrodes may be connected to the pulse generator to deliver the plurality of pulses to biological cells.
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