Method for producing influenza HA split vaccine

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United States of America Patent

PATENT NO 11732031
APP PUB NO 20190345231A1
SERIAL NO

16292065

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Abstract

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Provided is a method for producing an influenza HA split vaccine which produces an antibody that binds to a HA stem region of influenza, the HA stem region being less likely to cause antigenic variation, An influenza HA split vaccine is subjected to an acidic treatment. Through the acidic treatment, an influenza HA split vaccine which produces an antibody that binds to a LAH of the HA stem region is obtained. This influenza HA split vaccine has an excellent protective ability against infection of other influenza viruses of different antigenicity.

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Patent Owner(s)

Patent OwnerAddress
JAPAN AS REPRESENTED BY DIRECTOR GENERAL OF NATIONAL INSTITUTE OF INFECTIOUS DISEASES23-1 TOYAMA 1-CHOME SHINJUKU-KU TOKYO 1628640 JAPAN

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Adachi, Yu Tokyo, JP 12 1
Ato, Manabu Tokyo, JP 5 2
Takahashi, Yoshimasa Tokyo, JP 32 220

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