Rotavirus inner capsid subunit preparations

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United States of America Patent

PATENT NO 4190645
SERIAL NO

05938230

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Abstract

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A preparation of rotavirus inner capsid antigenic subunits which is substantially free from complete virus particles and fragments thereof. The subunits have a sedimentation coefficient of 17.5S, and a molecular weight of >2.times.10.sup.5 and >2.times.10.sup.6. Such a preparation can be prepared by suspending a sample of faecal material obtained from a mammal infected with rotavirus, incubating the suspension followed by the removal and concentration of the subunits from the suspension by centrifugation and/or filtration. Such a preparation is useful in several immunological tests and for the preparation of antisera also for use in tests.

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Patent Owner(s)

  • BURROUGHS WELLCOME CO.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Almeida, June D London, GB2 3 62

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