Calcium peroxides nanoparticles as adjuvant therapy

Number of patents in Portfolio can not be more than 2000

United States of America

PATENT NO 11235000
APP PUB NO 20200069727A1
SERIAL NO

16610151

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Abstract

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The invention provides CaO2 nanoparticles having a pH-responsive coating for use in a method of adjuvant therapy of hypoxic tumour cells or tissues. The nanoparticles find particular use in enhancing cancer therapies that depend on oxygen to exert their effect, such as photodynamic therapy (PDT), sonodynamic therapy (SDT), and radiotherapy. The invention also provides pharmaceutical compositions containing the coated CaO2 nanoparticles, together with at least one photosensitiser, sonosensitiser, or radiosensitiser and, optionally, at least one pharmaceutical carrier or excipient.

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Patent Owner(s)

  • UNIVERSITY OF ULSTER

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Callan, John Ballycastle Antrim, GB 8 9
Mchale, Anthony Ballycastle Antrim, GB 10 39
Sheng, Yingjie Coleraine Londonderry, GB 1 0

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