3-oxo-6-heteroaryl-2-phenyl-2,3-dihydropyridazine-4-carboxamides

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United States of America Patent

PATENT NO 11591311
APP PUB NO 20200283402A1
SERIAL NO

16765806

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention covers 3-oxo-6-heteroaryl-2-phenyl-2,3-dihydropyri-dazine-4-carboxamide compounds of general formula (I): in which R1, R2, R4, R5, R6, X, Y and Z are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of cancer or conditions with dysregulated immune responses or other disorders associated with aberrant AHR signaling, as a sole agent or in combination with other active ingredients.

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Patent Owner(s)

  • BAYER AKTIENGESELLSCHAFT; BAYER PHARMA AKTIENGESELLSCHAFT; DEUTSCHES KREBSFORSCHUNGSZENTRUM

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bader, Benjamin Berlin, DE 54 186
Carretero, Rafael Heidelberg, DE 6 0
Gutcher, Ilona Berlin, DE 8 0
Kober, Christina Lollar, DE 8 0
Platten, Michael Heidelberg, DE 20 18
Röhn, Ulrike Berlin, DE 19 2
Röse, Lars Berlin, DE 12 0
Stöckigt, Detlef Potsdam, DE 31 18
Zorn, Ludwig Berlin, DE 56 360

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