Treatment of chronic kidney disease and other renal dysfunction using a GDF15 modulator

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United States of America Patent

PATENT NO 11897948
APP PUB NO 20190292252A1
SERIAL NO

16179166

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Abstract

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The invention provides methods and compositions for treating a subject having a renal-related disorder, such as chronic kidney disease (CKD), end stage renal failure, diabetes, insulin resistance, kidney hypertrophy, kidney hypotrophy, polycystic kidney disease, proteinuria, hyperglycemia, hyperuricemia, gout, kidney stones, hypertension or hypertensive nephropathy, dyslipidemia, anemia and/or reduced erythropoietin production, iron deficiency or hyperfiltration. The methods and compositions use or contain a composition that reduces or inhibits GDF15 activity.

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Patent Owner(s)

Patent OwnerAddress
AVEO PHARMACEUTICALS INC30 WINTER STREET BOSTON MA 02108

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gyuris, Jeno Lincoln, US 62 564
Lerner, Lorena Newton Centre, US 26 84

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