Methods of detecting umami tastant-sensitive cells which express heteromeric T1R1/T1R3 receptors

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United States of America Patent

PATENT NO 8802377
APP PUB NO 20130102010A1
SERIAL NO

13615778

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Abstract

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The present invention relates to the discovery that the T1R receptors assemble to form functional taste receptors. Particularly, it has been discovered that co-expression of T1R1 and T1R3 results in a taste receptor that responds to umami taste stimuli, including monosodium glutamate. Also, it has been discovered that co-expression of the T1R2 and T1R3 receptors results in a taste receptor that responds to sweet taste stimuli including naturally occurring and artificial sweeteners.

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Patent Owner(s)

  • SENOMYX, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Adler, Jon Elliot San Diego, US 127 4236
Echeverri, Fernando Chula Vista, US 49 1954
Li, Xiaodong San Diego, US 448 10547
O'Connell, Shawn Encinitas, US 82 3598
Staszewski, Lena San Diego, US 91 4559
Xu, Hong San Diego, US 245 3525
Zoller, Mark San Diego, US 57 2833
Zozulya, Sergey San Diego, US 100 4106

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