Compositions and methods for inhibiting EB-1-mediated microtubule stability

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United States of America Patent

PATENT NO 7803932
SERIAL NO

11487244

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Abstract

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This invention provides a recombinant nucleic acid which, when introduced in vivo into a mammalian cell endogenously expressing EB1, inhibits the expression of EB1 therein, thereby reducing the amount of stable microtubules in the cell.This invention further provides related compositions, nucleic acids, cells and methods.

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Patent Owner(s)

  • THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gundersen, Gregg G Tenafly, US 2 0
Wen, Ying San Diego, US 9 19

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