Dendrimer-based DNA extraction methods and biochips
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United States of America Patent
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Jul 10, 2007
Grant Date -
Jun 16, 2005
app pub date -
Aug 30, 2004
filing date -
Dec 16, 2003
priority date (Note) -
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status (Latency Note)
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Abstract
The present invention provides a dendrimer-based biochip, wherein a flow channel through which a solution containing biopolymer molecules is flowed is formed in the substrate of the biochip, a plurality of dendrimer molecules one end of each of which is bound to the walls of the flow channel are formed thereon, and probe biopolymer or antibody molecules are bound to the tips of the dendrimer molecules so that, if the probe biopolymer molecules are bound, then target biopolymer molecules can be captured by means of a complementary combination and, if the antibody molecules are bound, then protein can be extracted by means of antigen-antibody reaction, whereby biopolymers can be retrieved in a highly efficient manner.
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