Benzene derivatives, their preparation and pharmaceutical compositions in which they are present
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United States of America Patent
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Oct 11, 1994
Issued Date -
N/A
app pub date -
May 24, 1991
filing date -
Dec 30, 1988
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Abstract
The present invention relates to compounds of the formula ##STR1## in which: p1 R.sub.1 is hydrogen or a halogen atom; R.sub.2 is a cyclohexyl or a phenyl; R.sub.3 is a (C.sub.3 -C.sub.6) cycloalkyl; R.sub.4 is hydrogen, (C.sub.1 -C.sub.6) alkyl or (C.sub.3 -C.sub.6)cycloalkyl; A is --CO--CH.sub.2 --, --CH(CI)--CH.sub.2 --, --CH(OH)--CH.sub.2 --, CH.sub.2 --CH.sub.2 --, --CH.dbd.CH-- and --C.tbd.C--, or their addition salt with mineral or organic acids. These compounds are active on the immune system. The present invention further relates to a method of preparing said compounds and to the pharmaceutical compounds in which they are present.
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