Nucleic acid separation

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United States of America Patent

PATENT NO 11253857
APP PUB NO 20210121883A1
SERIAL NO

16605927

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Abstract

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An example system includes an input channel to flow nucleic segments therethrough, a mixing portion coupled to the input channel, a separation chamber in fluid communication with the second end of the input channel, at least two output channels coupled to the chamber, and an integrated pump to facilitate flow through the separation chamber. The mixing portion is to include at least two different categories of beads having different sizes from each other and having a probe to attach to a corresponding nucleic acid segment. The separation chamber has a passive separation structure including an array of columns spaced apart to facilitate separation of the different categories of beads and attached corresponding nucleic acid segment into at least two flow paths based on a size of the category of the beads. Each output channel is to receive separated categories of beads and attached nucleic acid segments.

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Patent Owner(s)

  • HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Govyadinov, Alexander Corvallis, US 224 1099
Shkolnikov, Viktor Palo Alto, US 140 94

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