Pyrrolopyridazine JAK3 inhibitors and their use for the treatment of inflammatory and autoimmune diseases

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United States of America Patent

PATENT NO 8987268
APP PUB NO 20140011800A1
SERIAL NO

14005568

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Abstract

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The present invention provides compounds of formula I and pharmaceutically acceptable salts thereof. The formula I compounds inhibit tyrosine kinase activity of JAK3, thereby making them useful for the treatment of inflammatory and autoimmune diseases.

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Patent Owner(s)

  • BRISTOL-MYERS SQUIBB COMPANY

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Das, Jagabandhu Mercerville, US 87 965
Duan, Jingwu Yardley, US 56 473
Guo, Junqing Princeton, US 26 248
Hynes, John Washington Crossing, US 73 545
Jiang, Bin Norristown, US 168 706
Kempson, James Princeton, US 11 49
Lin, Shuqun Newtown, US 21 192
Lu, Zhonghui King of Prussia, US 21 127
Pitts, William J Newtown, US 51 919
Spergel, Steven H Warrington, US 46 481
Wrobleski, Stephen T Flemington, US 59 710
Wu, Hong New Hope, US 85 484
Yang, Bingwei Vera Belle Mead, US 24 182

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