Biodegradable implant for fracture nonunions

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United States of America Patent

PATENT NO 5492697
SERIAL NO

08403513

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A biodegradable implant for placement in nonunion bone fractures as a substitute for bone graft material is provided which is a flat plate or disk having a thickness of between about 1 mm and about 15% of the length of the bone, interconnected micropores, and canals substantially equivalent in size and spacing to naturally-occurring Haversian canals. The implant may additionally comprise additives such as growth factors, including bone morphogenic protein. In a preferred embodiment the implant is formed from a biodegradable polymer such as a polylactic acid-polyglycolic acid copolymer by a gel casting technique followed by solvent extraction to precipitate the implant as a microporous solid.

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Patent Owner(s)

  • BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Agrawal, Chandra M San Antonio, TX 1 160
Boyan, Barbara D San Antonio, TX 28 2634
Heckman, James D San Antonio, TX 3 434

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