Activators of autophagic flux and phospholipase d and clearance of protein aggregates including tau and treatment of proteinopathies

Number of patents in Portfolio can not be more than 2000

United States of America

PATENT NO 11261199
APP PUB NO 20200216469A1
SERIAL NO

16818388

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Abstract

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The present application discloses compounds which are activators of autophagic flux and pharmaceutical compositions comprising said activators. It further discloses use of said compounds and pharmaceutical compositions in the treatment of neurodegenerative diseases, particularly proteinopathies and tauopathies such as Alzheimer's disease. It further discloses methods of enhancing autophagic flux.

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Patent Owner(s)

  • THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK; NY STATE PSYCHIATRIC INSTITUTE

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Deng, Shi-Xian White Plains, US 36 110
Duff, Karen New York, US 12 30
Landry, Donald New York, US 27 75
Rinderspacher, Kirsten Alison Mount Vernon, US 13 5
Yu, Wai New York, US 7 5

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