Universal immune receptor expressed by T cells for the targeting of diverse and multiple antigens

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United States of America Patent

PATENT NO 11912753
APP PUB NO 20210317182A1
SERIAL NO

17353414

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Abstract

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The invention provides compositions and methods for adoptive T cell therapy in treating a variety of disorders including cancer, infections, and autoimmune disorders. In one embodiment, the invention provides a universal immune receptor (UnivIR) that comprises an extracellular label binding domain, a transmembrane domain, and a cytoplasmic domain or otherwise an intracellular domain.

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Patent Owner(s)

  • THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Powell,, Jr Daniel J Bala Cynwyd, US 31 740
Scholler, Nathalie Narberth, US 26 437
Urbanska, Katarzyna Philadelphia, US 7 15

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