Analogs of 3-amino-4-(propan-2-ylidene)cyclopentane-1-carboxylic acid and uses thereof for treating diseases and disorders associated with ornithine aminotransferase activity

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United States of America

PATENT NO 11203596
APP PUB NO 20200299296A1
SERIAL NO

16800753

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Abstract

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Disclosed are compound and methods of using the compounds for modulating ornithine aminotransferase (OAT) activity. The disclosed compound are characterized as analogs of 3-amino-4-(propan-2-ylidene)cyclopentane-1-carboxylic acid which may be formulated as therapeutic agents for treating diseases and disorders associated with ornithine aminotransferase (OAT) activity such as hepatocellular carcinoma and other cancers.

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Patent Owner(s)

  • NORTHWESTERN UNIVERSITY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Moschitto, Matthew J Evanston, US 1 0
Silverman, Richard B Winnetka, US 119 793

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