Methods for enhancing efficacy of therapeutic immune cells

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United States of America Patent

PATENT NO 11679132
APP PUB NO 20220347219A1
SERIAL NO

17862721

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to a method of using a receptor (e.g., chimeric antigen receptor—CAR) that activates an immune response upon binding a cancer cell ligand in conjunction with a target-binding molecule that targets a protein or molecule for removal or neutralization to generate enhanced anti-cancer immune cells. The present invention also relates to engineered immune cells having enhanced therapeutic efficacy and uses thereof.

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Patent Owner(s)

  • INSTITUTE OF MICROELECTRONICS NATIONAL UNIVERSITY OF SINGAPORE

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Campana, Dario Singapore, SG 49 973
Kamiya, Takahiro Singapore, SG 22 112

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