Methods and kits for detection of blast brain injury, its severity, distance from blast epicenter, and classification relative to the larger spectrum of concussion

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United States of America Patent

PATENT NO 11937935
APP PUB NO 20210030349A1
SERIAL NO

16966181

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Abstract

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The present disclosure is directed to the first methods and systems for diagnosing a patient being affected by a brain injury from a blast with greater accuracy that previous methods. The methods and system include an automated, non-invasive method for assessing the variance of a patient's ocular motility relative to a matched cohort of unaffected subjects, and using the variance in one or more ocular motility metrics to calculate a score that indicates a likelihood that the patient suffers from a blast brain injury. The score, referred to as a BIS, discriminates between affected an unaffected subjects with a sensitivity of greater than about 85%, a specificity of greater than 75%. The ROCAUC of the BIS is greater than 0.85.

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Patent Owner(s)

  • HENNEPIN HEALTHCARE SYSTEM, INC

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bin, Zahid Abdullah Minneapolis, US 1 0
Samadani, Uzma Minneapolis, US 18 94

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