Oral pharmaceutical composition for soft capsules containing vinorelbine and method of treatment
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United States of America Patent
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Feb 9, 2010
Grant Date -
Jul 28, 2005
app pub date -
Mar 18, 2005
filing date -
May 31, 2002
priority date (Note) -
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status (Latency Note)
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Abstract
The invention described herein relates to a pharmaceutical composition containing vinorelbine as an active ingredient which is suitable for encapsulation in soft capsules. The liquid oral pharmaceutical composition suitable for a liquid fill composition for a soft capsule dosage form comprises: vinorelbine or a pharmaceutically acceptable salt thereof; ethanol; water; glycerol; and polyethylene glycol. In a preferred embodiment, the tartrate salt form of vinorelbine is used in the composition. The invention also provides for a method of treating cancer comprising orally administering, to a patient in need of treatment thereof, a soft capsule comprising the pharmaceutical composition of the invention.
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