4,5-Deoxymaytansinoids, their use and pharmaceutical compositions thereof
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United States of America Patent
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Feb 1, 1983
Grant Date -
N/A
app pub date -
Sep 29, 1981
filing date -
Oct 8, 1980
priority date (Note) -
Expired
status (Latency Note)
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Abstract
This invention relates to 4,5-deoxymaytansinoid compounds represented by the formula ##STR1## wherein X is a hydrogen atom or an alkyl or acyl group, Y is a hydrogen or chlorine atom, and R is a hydrogen atom or a carboxylic acid-derived acyl group, and methods of producing the same. The compounds are useful as antitumor, antiprotozoal and antifungal agents.
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