Method for identifying an unknown allele
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United States of America Patent
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Dec 31, 2002
Grant Date -
N/A
app pub date -
Mar 31, 2000
filing date -
Nov 29, 1995
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
The invention provides a method for identifying an unknown allele of a polyallelic gene, which method comprises (i) contacting the unknown allele with a panel of probes, each of which recognises a sequence motif that is present in some alleles of the polyallelic gene but not in others; (ii) observing which probes recognise the unknown allele so as to obtain a fingerprint of the unknown allele; and (iii) comparing the fingerprint with fingerprints of known alleles. The use of a panel of probes which each recognises a different motif allows identification of which motifs are present in the unknown allele. The alleles of the polyallelic gene each have a unique combination of motifs and so identification of this combination (or 'fingerprint') leads to identification of the unknown allele.
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