Integrated device with external light source for probing detecting and analyzing molecules

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United States of America Patent

PATENT NO 11428635
APP PUB NO 20180328850A1
SERIAL NO

16028159

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Abstract

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Apparatus and methods for analyzing single molecule and performing nucleic acid sequencing. An integrated device includes multiple pixels with sample wells configured to receive a sample, which, when excited, emits radiation; at least one element for directing the emission radiation in a particular direction; and a light path along which the emission radiation travels from the sample well toward a sensor. The apparatus also includes an instrument that interfaces with the integrated device. Each sensor may detect emission radiation from a sample in a respective sample well. The instrument includes an excitation light source for exciting the sample in each sample well.

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Patent Owner(s)

  • QUANTUM-SI INCORPORATED

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bellofiore, Anthony Glastonbury, US 8 141
Cipriany, Benjamin Branford, US 41 642
Ferrigno, Michael Farmington, US 11 152
Glenn, Paul E Wellesley, US 51 605
Gyarfas, Brett J Guilford, US 27 579
Jewell, Jack Boulder, US 27 364
Kabiri, Ali Madison, US 51 609
Lackey, Jeremy Guilford, US 69 854
Rothberg, Jonathan M Guilford, US 554 35427
Schmid, Gerard Guilford, US 92 920
Sickler, Jason W Madison, US 45 805
West, Lawrence C San Jose, US 92 1668

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