Conversion of thebaine to morphine derivatives

United States of America Patent

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Apr 19, 2011
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Jan 1, 2009
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Jun 29, 2007
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Jun 29, 2007

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Abstract

The present invention provides methods for the conversion of thebaine to a morphine derivative, such as hydrocodone. Novel ketal intermediates of the conversion are provided. A one-pot procedure for the conversion comprises treating thebaine with an acid in the presence of a metal catalyst.

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BROCK UNIVERSITY

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C07D:HETEROCYCLIC COMPOUNDS

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Inventor Name	Address	# of filed Patents	Total Citations
Carroll, Robert James	St. Catharines, CA	5	69
Hudlicky, Tomas	St. Catharines, CA	33	174
Leisch, Hannes	St. Catharines, CA	6	59

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Conversion of thebaine to morphine derivatives

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United States of America Patent

11771259

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PATENT NO	7928234
APP PUB NO	20090005563A1
SERIAL NO	11771259
DOCKET NO

US Family Size	Non-US Coverage
Patent Longevity	Forward Citations

DATE PUBLISHED	PUBLICATION/PATENT NO.	PUBLICATION TYPE
April 19, 2011	US,7928234,B2 US7928234B2	GRANTED PATENT AS SECOND PUBLICATION
January 01, 2009	US,20090005563,A1 US20090005563A1	FIRST PUBLISHED PATENT APPLICATION

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11771259

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