Desmetylolanzapine compositions and methods
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United States of America Patent
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Feb 19, 2002
Grant Date -
N/A
app pub date -
Nov 22, 1999
filing date -
Nov 23, 1998
priority date (Note) -
Expired
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Abstract
Methods and compositions are disclosed utilizing N-desmethylolanzapine for the treatment of psychosis in humans. N-Desmethylolanzapine exhibits a lessened liability toward drug-drug interactions than olanzapine and a more predictable dosing regimen than olanzapine. N-Desmethylolanzapine is also useful for the treatment of acute mania, mild anxiety states, anxiety disorders, schizophrenia, bipolar disorder, attention deficit hyperactivity disorder, autistic disorder, excessive aggression, substance abuse, depressive signs and symptoms, tic disorder, functional bowel disorder and fungal dermatitis.
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