Methods for preparing and using highly active blood coagulation factor XI mutant and gene therapy/editing vector and recombinant/fusion protein thereof

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United States of America Patent

PATENT NO 11913042
APP PUB NO 20210207115A1
SERIAL NO

16771700

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Abstract

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Methods of preparing and using a highly active blood coagulation factor XI mutant and a gene therapy/editing vector thereof and a recombinant/fusion protein thereof. The nucleotide sequence of the mutant is as shown in SEQ ID NOs: 1-6, and the amino acid sequence is as shown in SEQ ID NO: 7.

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Patent Owner(s)

  • RUIJIN HOSPITAL, SHANGHAI JIAOTONG UNIVERSITY SCHOOL OF MEDICINE

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ding, Qiulan Shanghai, CN 2 0
Wang, Xuefeng Shanghai, CN 124 507
Wu, Wenman Shanghai, CN 2 0

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