Methods of identifying agents that diminish cellular toxicity associated with an .alpha.-synuclein polypeptide of Parkinson's disease in yeast

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United States of America Patent

PATENT NO 7452670
APP PUB NO 20050255450A1
SERIAL NO

11003216

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Abstract

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Methods of screening candidate agents to identify lead compounds for the development of therapeutic agents for the treatment of a neurodegenerative disease, such as Huntington's Disease and Parkinson's Disease and methods for identifying a mutation in, or changes in expression of, a gene associated with neurodegenerative disease, such as Huntington's Disease and Parkinson's Disease, are provided.

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Patent Owner(s)

  • UNIVERSITY OF WASHINGTON;WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Lindquist, Susan L Chestnut Hill, MA 34 239
Muchowski, Paul J Kenmore, WA 10 65
Outeiro, Tiago Cambridge, MA 9 77

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