Method for producing dendritic cells
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United States of America Patent
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Jul 24, 2007
Grant Date -
Feb 14, 2002
app pub date -
May 4, 2001
filing date -
Nov 5, 1998
priority date (Note) -
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Abstract
Disclosed are embryonic stem cell-derived dendritic cells, genetically modified immature dendritic cells capable of maturation, as well as methods for the production of such cells. In one embodiment, the cells made be produced by a method comprising the steps of providing a population of embryonic stem cells; culturing the embryonic stem cells in the presence of a cytokine or combination of cytokines which brings about differentiation of the embryonic stem cells into dendritic cells; and recovering the dendritic cells from the culture. In a further embodiment, the cells may be genetically modified.
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