Recognition of tumor-specific gene products in cancer

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United States of America Patent

PATENT NO 6686165
SERIAL NO

09752635

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention relates to the field of cancer diagnosis and the application of diagnostic techniques in pathology and hematology. Specifically, the invention relates to flow cytometric techniques for the detection of chromosomal aberrations and the detection of tumor specific gene products exclusively expressed by tumor cells containing said chromosomal aberrations. The invention provides a method to detect chromosomal aberrations in a biological sample via the exclusive detection of tumor-specific gene-product using at least two different probes directed against the gene-product.

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Patent Owner(s)

  • ERASMUS UNIVERSITEIT ROTTERDAM

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Berendes, Paulus Benjamin Heerlen, NL 2 12
van, Denderen Adriana Cornelia Gouda, NL 2 12
van, der Velden Vincent Henricus Johannes Capelle aan den IJssel, NL 8 21
van, Dongen Jacobus Johannes Maria Nieuwerkerk aan den IJssel, NL 23 155

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