Reduced size self-delivering RNAi compounds

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United States of America Patent

PATENT NO 8796443
SERIAL NO

13120342

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Abstract

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The present invention relates to RNAi constructs with minimal double-stranded regions, and their use in gene silencing. RNAi constructs associated with the invention include a double stranded region of 8-14 nucleotides and a variety of chemical modifications, and are highly effective in gene silencing.

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Patent Owner(s)

Patent OwnerAddress
PHIO PHARMACEUTICALS CORP257 SIMARANO DRIVE SUITE 101 MARLBOROUGH MA 01752

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cardia, James Franklin, US 27 1180
Kamens, Joanne Newton, US 34 1798
Khvorova, Anastasia Westborough, US 368 9372
Salomon, William Worcester, US 31 1641
Samarsky, Dmitry Westborough, US 39 1422
Woolf, Tod M Sudbury, US 60 2984

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