Oral antibacterial compositions and method for the improvement of gastrointestinal absorption of penem or carbapenem antibiotics
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United States of America Patent
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Oct 11, 1994
Grant Date -
N/A
app pub date -
Jan 31, 1992
filing date -
Feb 1, 1991
priority date (Note) -
Expired
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Abstract
Oral antibacterial compositions contain a penem or carbapenem antibiotic in combination with an absorption improver selected from substances capable of inhibiting the dipeptidase localized on/in epithelial cells of the small intestine, cilastatin, glutathione and N-acetyl-L-cysteine. Gastrointestinal absorption of the penem or carbapenem antibiotic can be improved by orally administering the absorption improver in combination with the antibiotic.
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