Method for improving morbid dermatitis by inhibiting activity of a plasminogen activator in the skin
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United States of America Patent
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Nov 18, 2003
Issued Date -
N/A
app pub date -
Jul 25, 2002
filing date -
Dec 24, 1999
priority date (Note) -
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Abstract
The present invention relates to a plasminogen activator inhibitor, an external preparation for skin comprising the same, a method for improving rough skin and in particular, for improvement of an effective inorganic component. A plasminogen activator inhibitor contains a specific zinc oxide which adsorbs a plasminogen activator and effectively inhibits its activity. When it is used as an external preparation for skin, excellent improvement of rough skin is obtainable. Further, when silica-coated zinc oxide is applied as an external preparation for skin, excellent improvement effect and prevention effect for rough skin are obtainable without an intolerance sensitivity reaction in the case of morbid dermatitis such as atopic dermatitis or pimpled skin.
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