RNAi modulation of the BCR-ABL fusion gene and uses thereof
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United States of America Patent
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Aug 9, 2011
Grant Date -
Sep 16, 2010
app pub date -
Jul 27, 2009
filing date -
Nov 24, 2004
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Abstract
The invention relates to compositions and methods for modulating the expression of Bcr-Abl, and more particularly to the down-regulation of Bcr-Abl mRNA and Bcr-Abl protein levels by oligonucleotides via RNA interference, e.g., chemically modified oligonucleotides.
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