Biosensor platform and method for the simultaneous, multiplexed, ultra-sensitive and high throughput optical detection of biomarkers

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United States of America Patent

PATENT NO 11519843
APP PUB NO 20200319085A1
SERIAL NO

16839138

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Abstract

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Biosensing platform for simultaneous, multiplexed, high throughput and ultra-sensitive optical detection of biomarkers labelled with plasmonic nanoparticles, the platform being provided with a biosensor, a broadband and continuous spectrum illumination source, an optical detector for simultaneously capturing spatially resolved and spectrally resolved the scattering signal of each individual nanoparticle, an autofocus system and an optical system adapted to collect the scattered signal of the biosensor's surface onto the optical detector, the platform being provided with translation means for the optical system and/or the biosensor, such that the optical system and the biosensor can be displaced relative to each other in the three dimensions, and wherein the processing means are adapted to: i) simultaneously capture spatially and spectrally resolved scattering signals from each nanoparticle individually, and ii) to analyze these signals simultaneously with the capture process.

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Patent OwnerAddress
MECWINS S A28760 TRES CANTOS (MADRID)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ahumada, Heredero Jesús Oscar Madrid, ES 2 0
Cebrián, Hernando Virginia Madrid, ES 2 0
García, Aguado Carlos Madrid, ES 2 0
Pini, Valerio Madrid, ES 7 6
Salvador-Matar, Renteria Antonio Madrid, ES 2 0
Thon, Andreas Madrid, ES 21 262

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