Substituted pyrazolo[3,4-d] pyrimidinones as a mitotic kinesin inhibitor

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United States of America Patent

PATENT NO 7262186
APP PUB NO 20050176737A1
SERIAL NO

10497385

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Abstract

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The present invention relates to azolopyriniidinone compounds that are useful for treating cellular proliferative diseases, for treating disorders associated with KSP kinesin activity, and for inhibiting KSP kinesin. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals.

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Patent Owner(s)

  • MERCK SHARP & DOHME CORP.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fraley, Mark E North Wales, PA 89 1006
Hartman, George D Lansdale, PA 194 3462
Hoffman, William F Lansdale, PA 66 1482

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